Heart blood flow image.  Heart blood flow refers to the movement of blood through the heart and blood vessels. Blood flows from the body into the right atrium, which then pumps it into the right ventricle. The right ventricle then pumps the blood into the lungs, where it receives oxygen and gets rid of carbon dioxide.  The oxygenated blood then returns to the left atrium and is pumped into the left ventricle.  The left ventricle is the main pumping chamber of the heart and pumps the oxygenated blood out to the rest of the body, where it supplies the tissues with oxygen and other essential nutrients. The heart blood flow is regulated by the autonomic nervous system.  This adjusts the heart rate and blood pressure based on the body's needs. Blood flow through the heart can also be affected by factors such as physical activity, stress, and changes in blood pressure or blood volume.  An interruption in heart blood flow, such as a heart attack or blockage in the blood vessels, can lead to serious health problems and may require medical intervention.