Bone osteoblast close up video. Bones are rigid organs that forms the skeleton of the body. Bones are made up of a framework of a protein called collagen and a mineral called calcium phosphate which makes the framework hard and strong. The 206 bones in the human body support and protect internal organs.for example, the skull protects the brain and the ribs protect the lungs). They function to move, support, and protect the various organs of the body, produce red and white blood cells and store minerals. Osteoclasts are the cells responsible for bone resorption (remodeling of bone to reduce its volume). Osteoclasts are large, multinucleated cells located on bone surfaces in what are called Howship's lacunae or resorption pits. Bone videos from medical animation experts Polymime.